Philadelphia 76ers (7-1, first in the Eastern Conference) vs. Detroit Pistons (6-1, second in the Eastern Conference)

Detroit; Wednesday, 7 p.m. EST

LINE: Pistons -1.5; over/under is 219.5

BOTTOM LINE: The Detroit Pistons host the Philadelphia 76ers.

Detroit went 60-22 overall, 39-13 in Eastern Conference action and 32-9 at home during the 2025-26 season. The Pistons averaged 117.8 points per game last season, 57.9 in the paint, 21.4 off of turnovers and 18.0 on fast breaks.

Philadelphia finished 45-37 overall and 27-25 in Eastern Conference play during the 2025-26 season. The 76ers averaged 115.9 points per game while allowing opponents to score 116.1 last season.

The teams square off for the second time this season. The Pistons won 106-93 in the last matchup on Oct. 25. Cade Cunningham led the Pistons with 26 points, and Tyrese Maxey led the 76ers with 29 points.

INJURIES: Pistons: Jalen Duren: out (hamstring), Isaiah Joe: out (hip).

76ers: Ariel Hukporti: out for season (achilles), Dominick Barlow: out (back).

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The Associated Press created this story using technology provided by Data Skrive and data from Sportradar.